Plasma Technology Laboratory
Department of Chem. Engineering
Contact details:
Assoc. Professor: D. Mataras
e-mail: dim@plasmatech.gr
Tel: +30-2610969525
Fax: +30-2610993361
url: www.plasmatech.gr
Role in the project: Partner

Group Description
Research area: Preperation and characterization of biomaterials using plasma based
treatment and deposition techniques. In the network, PTL participates in the training,
dissemination and network sustainability activities. The lab facilities include five plasma
reactors (Capacitively Coupled, Inductively Coupled, Electron Cyclotron Wave
Resonance) several in-situ plasma diagnostics techniques available (optical, electrical,
interferometric, mass spectrometric measurements) and for material characterization:
Scanning probe microscope, contact angle goniometer and a near field optical microscope.
The team contributing to the network from PTL includes: Prof. Dimitrios Mataras who is a
well known scientist in the field of advanced methods for the plasma treatment and plasma
coating of a wide variety of materials with an application field ranging from
microelectronics to biomaterials including the protective nano-coatings that are at the
core of the proposed research. In addition, one research fellow (Dr E. Amanatides) and two
PhD students will contribute to the different project activities. A more detailed presentation of PTL activities can be found here
Liposome Research Laboratory
Lab. Pharmaceutical Technology
Department of Pharmacy
Contact details:
Asoc. Professor: S. Antimisiaris
e-mail: santimis@upatras.gr
Tel: +30-2610969332
Fax: +30-2610996302
Role in the project: Partner

Group Description
Research area: Design and development of advanced nanoparticulate systems for
controlled delivery and targeting of bioactive substances or drugs (nanomedicines).
In the network, LRL participates in the training, dissemination and network sustainability
activities. The group is equipped with several devices/equipment for preparation and
evaluation of Nanoparticulate (NP) drug carriers (probe and bath Sonicators (Sonics and
Materials, Branson), Extrusion systems (Avestin), Rotor evaporators, Thermostated Bath
Incubators); Equipment for measurement of drug loading, physicochemical
characterization and cytotoxicity/ uptake by cells of NPs (UV-VIS Spectrophotometers,
Fluorimeters, centrifuge, ultracentrifuge, HPLC -gradient systems, FPLC systems, DSC,
Incubators, Fluorescent Microscope (Leica), cell culture facility room [Laminar flow Hood
(Holten), CO2 Incubator (Forma Scientific)]).
Key Persons: Prof. Sophia G. Antimisiaris, who is a well known scientist in the area of novel
drug delivery and targeting systems and nanoliposome technology; Assistant Professor
Pavlos Klepetsanis, with >20 years of experience in physicochemical characterization of
drug frormulations and Dr. Spyros Mourtas, with > 10 years experience in organic
synthesis and functionalization reactions will be also involved in the actions. A more detailed description of LRL activities can be found here
In the network are involved nine groups from five departments (Dept. of Mechanical
Engineering
, Dept. of Chemical Engineering, Dept. of Biology, Dept. of Pharmacy, Dept of
Medicine
) and three schools (Polytechnique, Physical Sciences and Health Sciences) from
the University of Patras, covering a wide research area from materials preparation to in
vivo tests of biomedical devices.
A brief description of research activities of the groups, their role in the network and
contact details are given below:



Laboratory of Biomechanics and Biomedical Engineering
Department of Mechanical Engineering and Aeronautics
Contact details:
Professor: Yannis Misirlis
e-mail: misirlis@mech.upatras.gr
Tel: +30-2610997232, +30-2610969460
Fax: +30-2610969464
Role in the project: Coordinator

Group Description
The Laboratory of Biomechanics and Biomedical Engineering of the University of Patras (UPAT-BEL), Greece, directed by Pr. Y. Missirlis is staffed by 1 Associate Professor, 2 Assistant Professors, 1 post-doctoral research assistant and 5 PhD students. The main research areas are the study of tissue-materials interactions, mechanical and nanomechanical properties of cells, tissues and biomaterials as well as tissue engineering. The group coordinates the network and will participate in the project in educative, training, dissemination and administrate activities. The group have the experience and equipment to perform haemocompatibility and bacterial adhesion evaluation tests of existing and new developed materials following the ISO 10993-4 guidelines. Platelet adhesion and activation, activation of coagulation, complement and immune system and thrombus formation, as well as the number and the pattern of adherent bacteria can also be evaluated. Zeta sizer and goniometer are available for the physicochemical characterization of polymeric materials and bacteria. Cell-material interactions can be characterized using Scanning Electron, Atomic Force and Confocal Microscopy Microscopy. Materials surface morphology can also be evaluated before and after blood-biomaterial and bacterial-biomaterial contact using Atomic Force Microscopy. Mechanical and nanomechanical properties of cell, tissues and biomaterials can be evaluated using a Miniature Materials Tester and Nanoindentation technique.

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Research Laboratory of Pharmaceutical Biotechnology
and Molecular Diagnosis
Department of Pharmacy
School of medicine

Contact details:
Asoc. Professor: G. Sotiropoulou
e-mail: gdsotiro@upatras.gr
Tel: +30-2610-969939
Fax: +30-2610-969940
Role in the project: Partner

Group Description
Department of Microbiology
School of Medicine
Contact details:
Asoc. Professor: I. Spiliopoulou
e-mail: spiliopl@med.upatras.gr
Tel: +30-2610996111
Fax: +30-2610994922
Role in the project: Partner

Group Description
Research area: Molecular diagnostics of bacterial infections-virulent factors-molecular
fingerprinting-epidemiology.
In the network, the Microbiology group participates in the training, dissemination and
network sustainability activities. The group has all the knowledge, experience and
equipment for the characterization of bacteria by phenotypic and genotypic methods.
Clonal analysis, identification of genes encoding antimicrobial resistance genes, toxins and
pathogenicity islands among clinical bacterial isolates. Application of molecular methods
for the quantification of the expression of pathogenicity genes involved in the attachment
process and biofilm formation, under different bacterial growth conditions onto modified
materials. Analysis of the results in correlation to the application of biomaterials to
patients will be performed. Some of lab facilities are: Molecular diagnostics techniques and
equipment such as, simple PCR machine, hybridization oven, real-time PCR, DNA
sequencer, PFGE apparatus, simple electrophoresis systems and power supplies. This
equipment is applied in studying virulence and antibiotic resistance factors of bacteria in
vitro and directly into clinical specimens, expression of genes involved in bacterial
attachment, biofilm formation and toxins production by reverse-transcription Real-Time
PCR.
Key Persons: Prof. Iris Spiliopoulou who is a scientist in the field of molecular
epidemiology-fingerprinting and studying virulence and antibiotic resistance factors of
bacteria. A more detailed description of group activities can be found here
Department of Biology
School of Physical Sciences
Contact details:
Assoc. Professor: P. Katsoris
e-mail: katsopan@upatras.gr
Tel: +30-2610 969241
Fax: -
Role in the project: Partner

Group Description
Department of Surgery
School of Medicine
Contact details:
Professor: D. Alexopoulos
e-mail: dcalex@otenet.gr
Tel: +30-2610999281
Fax: +30-2610999281
Role in the project: Partner

Group Description
Research area: Arteries stenosis and histological evaluation of healing and toxicity
In the network, the surgery group participates in the training, dissemination and network
sustainability activities. The group has experience and all the necessary equipment for the
in-vivo tests of stents in animal models. The group equipment and methods can be used for
the evaluation of the area stenosis, the neointimal area, the neointimal thickness, and the
lumen area. In addition, histologically evaluation for healing and toxicity of arteries can be
also performed and factors as extra stent segments effects, and overall artery size, can also
be checked.
Key persons in the network: Professor Dimitrios Alexopoulos, assistant professor (Dr
Ioannis Chiliadakis)
Department of Surgery
School of Medicine
Contact details:
Assist. Professor: E. Liatsikos
e-mail: liatsikos@yahoo.com
Tel: +30-2610999281
Fax: +30-2610999281
Role in the project: Partner

Research area: Evaluation of polymeric and metallic prostate and ureter stents. Evaluation
of drug eluting stents. Evaluation of different laparoscopic surgical techniques.
In the network the group will participate in the training, dissemination and network
sustainability activities. The group has all the necessary experience, knowledge and
equipment for the in vivo evaluation of coated and drug eluting prostate and ureter stents
in small animals models.
Facilities: Complete experimental laparoscopic surgery lab
Key persons: Prof. Liatsikos is a well known scientist in the field of laparoscopic urology
with a large number of scientific presentations, patents and conferences announcements. A more detailed description of group activities can be found here
Department of Pathology
School of Medicine
Contact details:
Assoc. Professor: C. Fortounas
e-mail: cfortoun@usa.net
Tel: +30 2610 994649
Fax: -
Role in the project: Partner

Group Description
2nd workshop on advanced biomaterials
and biomedical applications

Friday 22 October 2010
Place: Conference & Cultural Center
of
the University of Patras

For more information visit our events page

1st workshop on advanced biomaterials
and biomedical applications

Check the summary of the event

2nd workshop on advanced biomaterials
and biomedical applications
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